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IGF Program

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Maize

SNPs
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Bioinformatics

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Information on genetic relationships among individuals is of importance to plant breeders for line and hybrid development. Estimates on the genetic similarity of breeding materials is best obtained using DNA markers. The most abundant genetic polymorphisms between individuals are Single Nucleotide Polymorphisms and small insertions/deletions, which are both emerging as a new generation of markers, due to their abundance and amenability to fully automated genotyping. SNPs (Single nucleotide polymorphisms) are single base pair positions at which different sequence alternatives exist between two individuals. There are six possible SNP types, either transitions (A<>T or G<>C) or transversions (A<>G, A<>C, G<>T or C<>T). We are developing methods for the discovery of SNPs within and between cereal genomes, along with methods for the high throughput detection of SNPs using a Single Nucleotide Primer Extension (SNuPe) assay.

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Maintained by Gary Barker Last updated Jan 2007